年中总结 | 普罗亭2023年上半年学术成果特辑
年中·总结
2023上半年普罗亭学术成果一览
|
合作单位 |
文章标题 | 研究内容 | 发表期刊 | 影响因子 |
|---|---|---|---|---|
|
浙江大学 |
Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design |
单细胞多组学技术鉴定一种IL-1受体突变驱动的自身免疫性疾病并指导指导IL-1的药物设计 |
Immunity |
43.474 |
|
深圳肿瘤医院 |
Epigenetic reprogramming of RUNX3 reinforces CD8+T-cell function and improves the clinical response to immunotherapy |
单细胞分析揭示RUNX3的表观遗传重编程增强了CD8+t细胞的功能，并提高了对免疫治疗的临床反应 |
Mol Cancer |
41.444 |
|
复旦大学附属中山医院 |
Disruption of SLFN11 deficiency-induced CCL2 signaling and macrophage M2 polarization potentiates anti-PD-1 therapy efficacy in hepatocellular carcinoma |
单细胞多组学技术发现SLFN11缺陷诱导的CCL2信号传导和巨噬细胞M2极化的破坏增强了肝细胞癌的抗PD-1治疗效果 |
Gastroenterology |
33.885 |
|
浙江大学附属第二医院 |
Single-cell Profiling of Tumor Immune Microenvironment Reveals Immune Irresponsiveness in Gastric Signet-ring Cell Carcinoma |
肿瘤免疫微环境的单细胞分析揭示胃印戒细胞癌的免疫无反应 |
Gastroenterology |
33.885 |
|
中国人民解放军总医院 |
Decitabine-priming increases anti-PD-1 antitumor efficacy by promoting CD8+ progenitor exhausted T-cell expansion in tumor models |
地西他滨启动通过促进肿瘤模型中CD1+祖细胞耗尽的T细胞扩增来提高抗PD-8抗肿瘤的功效 |
J Clin Invest |
19.456 |
|
西南大学药学院医学研究所 |
Breaking Spatiotemporal Barriers of Immunogenic Chemotherapy via an Endoplasmic Reticulum Membrane-Assisted Liposomal Drug Delivery |
使用单细胞和多级分析来强调首次接触钙网蛋白 (CRT) 在引发免疫原性方面的重要性 |
ACS Nano |
18.027 |
|
浙江大学附属第一医院 |
An Ionic Liquid Ablation Agent for Local Ablation and Immune Activation in Pancreatic Cancer |
一种用于胰腺癌局部消融和免疫激活的离子液体消融剂 |
Adv Sci (Weinh) |
17.521 |
|
浙江大学医学院附属第一医院 |
Effects of 3-HAA on HCC by Regulating the HeterogeneousMacrophages—A scRNA-Seq Analysis |
单细胞多组学全面剖析3-HAA对HCC的影响及免疫调节作用 |
Adv Sci (Weinh) |
17.521 |
|
杭州市第一人民医院 |
SULT2B1-CS-DOCK2 axis regulates effector T cell exhaustion in hepatocellular carcinoma microenvironment |
SULT2B1-CS-DOCK2轴调节肝细胞癌微环境中效应T细胞耗竭 |
Hepatology |
17.298 |
|
北京协和医学院血液病研究所 |
Single-cell analysis highlights a population of Th17-polarized CD4 + naïve T cells showing IL6 / JAK3 / STAT3 activation in pediatric severe aplastic anemia |
单细胞分析突出显示了 Th17 极化 CD4 幼稚 T 细胞群，在小儿重度再生障碍性贫血中显示 IL6/JAK3/STAT3 活化+ |
J Autoimmun |
14.511 |
|
复旦大学附属中山医院 |
Intratumoral PPT1-positive macrophages determine immunosuppressive contexture and immunotherapy response in hepatocellular carcinoma |
单细胞多组学技术发现瘤内 PPT1 阳性巨噬细胞决定肝细胞癌的免疫抑制环境和免疫治疗反应 |
J Immunother Cancer |
13.75 |
|
浙江大学医学院附属第一医院 |
Single-cell analysis reveals HBV-specific PD-1+CD8+ TRM cells in tumor borders are associated with HBV-related hepatic damage and fibrosis in HCC patients |
单细胞分析显示肿瘤边界的HBV特异性PD-1+CD8+TRM细胞与HCC患者HBV相关的肝损伤和纤维化有关 |
Clin Cancer Res |
12.658 |
|
西南大学 |
Physical- and Chemical-Dually ROS-Responsive Nano-in-Gel Platforms with Sequential Release of OX40 Agonist and PD-1 Inhibitor for Augmented Combination Immunotherapy |
物理和化学二重ROS响应纳米凝胶平台，结合OX40激动剂和PD-1抑制剂的顺序释放，用于增强联合免疫治疗 |
Nano Lett |
12.262 |
|
深圳大学医学院过敏与免疫学研究所 |
Multidimensional Analysis of Lung Lymph Nodes in a Mouse Model of Allergic Lung Inflammation following PM2.5 and Indeno[1,2,3- cd ]pyrene Exposure
|
过敏性肺部炎症小鼠模型中肺淋巴结的多维分析PM2.5和茚并芘暴露 |
Environ Health Perspect |
11.035 |
|
北京大学深圳医院 |
Phenotypic and functional alteration of CD45+ immune cells in the decidua of preeclampsia patients analyzed by mass cytometry (CyTOF) |
通过质谱流式（CyTOF）分析先兆子痫患者蜕膜中CD45+免疫细胞的表型和功能改变 |
Frontiers in Immunolog |
8.786 |
|
浙江大学附属儿童医院 |
Comprehensive mapping of B lymphocyte immune dysfunction in idiopathic nephrotic syndrome children |
特发性肾病综合征患儿B淋巴细胞免疫功能障碍综合定位 |
Clin Transl Med |
8.554 |
|
鲁南制药有限公司 |
Shouhui Tongbian Capsules induce regression of inflammation to improve intestinal barrier in mice with constipation by targeted binding to Prkaa1: With no obvious toxicity |
首荟通便胶囊通过肠道微生物群-5-HT-肠蠕动轴改善便秘 |
Biomedicine & Pharmacotherapy |
7.419 |
|
浙江中医大学附属第一医院 |
Depiction of immune heterogeneity of peripheral blood from patients with type II diabetic nephropathy based on mass cytometry |
基于质谱细胞术的II型糖尿病肾病患者外周血免疫异质性描述 |
Front Endocrinol (Lausanne) |
6.055 |
|
广州中医药大学附属第二医院（广东省中医院） |
Single-Cell Analysis in Blood Reveals Distinct Immune Cell Profiles in Gouty Arthritis |
血液中的单细胞分析揭示痛风性关节炎中不同的免疫细胞谱 |
J Immuno |
5.426 |
|
兰州大学基础医学院 |
Carbon ion irradiation induces DNA damage in melanoma and optimizes the tumor microenvironment based on the cGAS–STING pathway |
碳离子照射诱导黑色素瘤DNA损伤，基于cGAS-STING通路优化肿瘤微环境 |
J Cancer Res Clin Oncol |
4.322 |
|
中国医学科学院北京协和医学院微循环研究所 |
Mass Cytometry Reveals the Imbalanced Immune State in the Peripheral Blood of Patients with Essential Hypertension |
质谱细胞术揭示原发性高血压患者外周血免疫状态不平衡 |
Cardiovasc Ther |
3.368 |
